Large-scale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid
CH Wu, HN Murthy, EJ Hahn, KY Paek - Biotechnology letters, 2007 - Springer
Adventitious roots of Echinacea purpurea were cultured in airlift bioreactors (20 l, 500 l
balloon-type, bubble bioreactors and 1,000 l drum-type bubble bioreactor) using Murashige
and Skoog (MS) medium with 2 mg indole butyric acid l− 1 and 50 g sucrose l− 1 for the
production of chichoric acid, chlorogenic acid and caftaric acid. In the 20 l bioreactor
(containing 14 l MS medium) a maximum yield of 11 g dry biomass l− 1 was achieved after
60 days. However, the amount of total phenolics (57 mg g− 1 DW), flavonoids (34 mg g− 1 …
balloon-type, bubble bioreactors and 1,000 l drum-type bubble bioreactor) using Murashige
and Skoog (MS) medium with 2 mg indole butyric acid l− 1 and 50 g sucrose l− 1 for the
production of chichoric acid, chlorogenic acid and caftaric acid. In the 20 l bioreactor
(containing 14 l MS medium) a maximum yield of 11 g dry biomass l− 1 was achieved after
60 days. However, the amount of total phenolics (57 mg g− 1 DW), flavonoids (34 mg g− 1 …
Large-scale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid
W Chun-Hua, HN Murthy, H Eun-Joo… - Biotechnology …, 2007 - search.proquest.com
Adventitious roots of Echinacea purpurea were cultured in airlift bioreactors (20 l, 500 l
balloon-type, bubble bioreactors and 1,000 l drum-type bubble bioreactor) using Murashige
and Skoog (MS) medium with 2 mg indole butyric acid l− 1 and 50 g sucrose l− 1 for the
production of chichoric acid, chlorogenic acid and caftaric acid. In the 20 l bioreactor
(containing 14 l MS medium) a maximum yield of 11 g dry biomass l− 1 was achieved after
60 days. However, the amount of total phenolics (57 mg g− 1 DW), flavonoids (34 mg g− 1 …
balloon-type, bubble bioreactors and 1,000 l drum-type bubble bioreactor) using Murashige
and Skoog (MS) medium with 2 mg indole butyric acid l− 1 and 50 g sucrose l− 1 for the
production of chichoric acid, chlorogenic acid and caftaric acid. In the 20 l bioreactor
(containing 14 l MS medium) a maximum yield of 11 g dry biomass l− 1 was achieved after
60 days. However, the amount of total phenolics (57 mg g− 1 DW), flavonoids (34 mg g− 1 …
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